Teriflunomide impurity 3
规格
| Cas Number | 1011244-72-6(DMSO) |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 过滤标签 | COX,Immunology/Inflammation,Compound libraries |
| 储存温度 | 避光,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | 特立氟胺杂质 3（4-氨基-N-（4-三氟甲基苯基）苯甲酰胺）是一种选择性 COX-1 抑制剂，IC 50 为 30 µM。特立氟胺杂质 3 对 COX-2 的活性较低（IC 50 >100 µM）。 |
| 英文描述 |
Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC 50 of 30 µM. Teriflunomide impurity 3 is less active against COX-2 (IC 50 >100 µM) In Vitro Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide; compound 11q) is an amide-bond-reversed compound bearing trifluoromethyl and amino substituents showed potent COX-1-selective inhibitory activity. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:COX-1 30 μM (IC 50 ) |