Thalidomide-Piperazine-PEG2-NH2 diTFA
规格
| Cas Number | T658999 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 100mg 或 50mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | H2O : 50 mg/mL (71.27 mM; Need ultrasonic) |
| 过滤标签 | E3 Ligase Ligand-Linker Conjugates,PROTAC |
| 储存温度 | 2-8°C储存,干燥 |
| 运输条件 | 冰袋运输 |
| 英文描述 |
Thalidomide-Piperazine-PEG2-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Appearance:Solid In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE Biological Activity:Thalidomide-Piperazine-PEG2-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |