XEN723
规格
| Cas Number | 1072803-08-7 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 50mg 或 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 100 mg/mL (235.03 mM; Need ultrasonic) |
| 过滤标签 | Stearoyl-CoA Desaturase (SCD),Metabolic Enzyme/Protease |
| 储存温度 | 避光,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | XEN723 是一种新型、强效的硬脂酰辅酶脱饱和酶（SCD1）噻唑基咪唑烷酮抑制剂，在小鼠和 HepG2 细胞中的 IC 50 s 分别为 45 和 524 nM。 |
| 英文描述 |
XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase ( SCD1 ) with IC 50 s of 45 and 524 nM in mouse and HepG2 cell, respectively. In Vitro XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC 50 s of 45 and 524 nM in mouse and HepG2 cell, respectively. XEN723 demonstrates an improvement in SCD1 in vitro potency of more than 560-fold compare to the original high throughput screen (HTS) hit. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 45 nM (SCD1 in Mouse), 524 nM (SCD1 in HepG2 cell) |