YSK 05
规格
| Cas Number | 1318793-78-0 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 100mg 或 50mg 或 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 过滤标签 | Liposome,Metabolic Enzyme/Protease,Ionizable Lipid |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | YSK 05 是一种对 pH 值敏感的阳离子脂质。YSK 05 可改善非病毒载体在细胞内的转运。YSK 05-MEND 具有明显的基因沉默活性和溶血活性。YSK 05 克服了 PEGyl 对内质体逃逸的抑制。 |
| 英文描述 |
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo. In Vitro YSK 05 facilitates the endosomal escape of the MEND and thereby enhances the efficacy of siRNA delivery into cytosol and gene silencing. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Liquid |