Z-YVAD-FMK
规格
Cas Number | 210344-97-1 |
规格或纯度 | ≥97% |
纯度 | ≥97% |
包装 | 50mg 或 10mg 或 1mg 或 5mg 或 25mg |
产品信息
品牌 | 阿拉丁 |
溶解性 | Solubility (25°C) In vitro DMSO: 100 mg/mL (158.56 mM); Water: Insoluble; Ethanol: Insoluble; |
简短描述 | Caspase-1 选择性抑制剂 |
英文简短描述 | Caspase-1 Selective Inhibitors |
过滤标签 | Apoptosis,Caspase,Caspase inhibitor |
储存温度 | -80℃储存 |
运输条件 | 超低温冰袋运输 |
生化和生理学机理 | Z-YVAD-FMK 是一种细胞渗透性和不可逆的 caspase-1 特异性抑制剂,具有抗炎和抗肿瘤活性。 |
英文描述 |
Information Z-YVAD-FMK is a cell-permeable and irreversiblecaspase-1specific inhibitor with anti-inflammatory and anti-tumor activities. Targets caspase-1 In vitro Z-YVAD-FMK treatment significantly reduces the increased caspase-1 activity induced by LPS+Aβ. Z-YVAD-FMK remarkably suppresses the protein expressions of cleaved IL-1β, cleaved IL-18, and Iba-1. Cell Research(from reference) Cell lines:BV2 cells Concentrations:5 μM Incubation Time:1 h |